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News
The fungal cell wall: an underused target for antifungal drugs.
The fungal cell wall is a protective structure outside the cell membrane, built mainly from glucans, chitin, and proteins. Human cells lack this structure, making the enzymes that build and maintain it attractive antifungal drug targets. Dfg5 and Dcw1 are…
Fungal infections need a new treatment strategy!
Fungal infections need new treatments because resistance is narrowing an already limited range of medicines, while toxicity and treatment complexity create additional barriers to care. New antifungal treatments must expand the mechanisms available to clinicians and address the needs of…